J.E. Liggett and Brother is established in St. Louis, Mo.
R.J. Reynolds Tobacco Company (better known for its Reynolds Wrap Aluminum Foil) was established to produce chewing tobacco.
3.5 billion cigarettes were sold, while 6 billion cigars were sold.
The British Phillip Morris sets up a New York headquarters to market its cigarettes, including a now famous Marlboro brand.
R.J. Reynolds began to market a cigarette brand called Camel.
Cigarette production was up to 300 billion a year. Service men received about 75% of all cigarettes produced.
Dr. Ernst L. Wynders finds that putting cigarette tar on the backs of mice causes tumors.